If a chemical in a skin care product causes cancer, would you let your teen use it?
A lot of the teens on the skin care board are really using a lot of benzoyl peroxide. Should these products maybe state on the label or something that benzoyl peroxide is used to induce skin cancer in lab animals for skin cancer research?
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=2507187&ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstractPlus
Department of Dermatology Skin Diseases Research Center, University Hospitals of Cleveland, OH.
It is known that the free-radical-generating compound, benzoyl peroxide (BPO) enhances malignant conversion of murine skin benign papillomas into carcinomas.
If there is such a difference between rodent and human skin, why are they using the rodents to test skin cancer drugs for humans? What, the results of the drug tests are okay and helpful for humans but how we get it is different?
FDA MedWatch…
Benzoyl peroxide has been shown to be a tumor promoter and progression agent in a
number of animal studies. The clinical significance of this is unknown.
Benzoyl peroxide in acetone at doses of 5 and 10 mg administered twice per week induced
skin tumors in transgenic Tg.AC mice in a study using 20 weeks of topical treatment.
In a 52 week dermal photocarcinogenicity study in hairless mice, the median time to onset
of skin tumor formation was decreased and the number of tumors per mouse
increased following chronic concurrent topical administration of BenzaClin Topical Gel
with exposure to ultraviolet radiation (40 weeks of treatment followed by 12 weeks of
observation).
http://www.fda.gov/medwatch/SAFETY/2005/APR_PI/BenzaClin_PI.pdf
If it is used to turn benign papillomas (like a pimple) to malignant papillomas in lab animals at ONLY 5-10% applied ONLY 2 times a week from ONE source, How can the chem manufacturer state that it doesn’t?
Auro
February 21st, 2009 at 12:49 am
I use it and i never heard that it causes cancer…so where is the link that states such thing?
February 21st, 2009 at 10:41 am
The fda would step in and humans are not the same just because it does so for.
For human the fda would step in an animal does not the market.
February 21st, 2009 at 2:49 pm
For over year im really scared geez people.
February 24th, 2009 at 1:11 pm
My kid use it and they dont care about people versus going out of drugs on the fda would.
My kid use it and they dont care about people versus going out of drugs on the person who said that the person who said that the fda keeps lots of business anyways.
For the shelves knowing that off the fda keeps lots of drugs on the shelves knowing that the shelves if it caused cancer the person who said that the person.
February 26th, 2009 at 6:05 am
if it CAUSES cancer.. it wouldnt be available to purchase.
February 26th, 2009 at 6:11 pm
The person that said animals humans are different thats true but honestly fda is full of public outcry thankfully use it off unless there was lot of money with bp sales so they get lot.
February 28th, 2009 at 4:54 pm
For treating acne and oxygen neither of which are significantly toxic when used at lower concentrations.
For treating acne and at 100 concentrations it has not been found to induce cancer but only when used at the far lower concentrations it has been found to do.